Xerocare Anti-Calluses Cream With 40% Urea, Allantoin & Shea Butter – 50ml

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Anti-Calluses Cream with 40% Urea, Allantoin & Shea Butter – 50ml, a powerful formula specially developed for thickened, cracked skin or areas affected by severe calluses. Clinically proven to help in cases of hyperkeratosis, this intensive cream softens, smooths, and supports skin regeneration on heels, soles, palms, or elbows. Not suitable for sensitive skin or for use on large areas of the body.

INGREDIENTS:

Aqua/Thermal Water, Urea, Glycerin, Butyrospermum Parkii Butter, Cetearyl Olivate, Sorbitan Olivate, Stearic Acid, Coco-Caprylate/Caprate, Caprylic/Capric Triglyceride, Phenoxyethanol, Allantoin, Tocopheryl Acetate, Ethylhexylglycerin, Disodium EDTA.

16,94 

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Independent Clinician Evaluations

Clinicians receive product samples and are never compensated to submit evaluations.

Chirea Alexandra

Chirea Alexandra

Verified clinician ✓

Specialty Senior Consultant in Dermatology and Venereology
Medical Institution Prima Clinic

Hydration and Repair

The Xerocare range from Synergy Therm contains urea in optimal concentrations and is recognized for its moisturizing, keratolytic, and reparative properties. The synergy of active ingredients delivers highly satisfying results for patients.
Highlights:
Active urea Dry skin Visible results
Iuliana Cristiana Cîrcu

Iuliana Cristiana Cîrcu

Verified clinician ✓

Specialty Senior Consultant in Dermatology and Venereology
Medical Institution Dr Skin Taberei

Repair & Quick Soothing

A special formula designed for thickened and cracked skin. It is excellent in the process of repairing and soothing the skin quickly, adding extra hydration with visible effects after just a few applications. You’ll love it instantly.
Highlights:
Soothes discomfort Repairs skin Visible effect
Marta Maria Miralena

Marta Maria Miralena

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Dermalife

Thick Skin Repair

Repairs thickened and cracked skin on heels, soles, palms, and elbows.
Highlights:
Cracked heels Palms Elbows
Buzilă Sanda

Buzilă Sanda

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Revive Medical

Complete Care for Dry Skin

The Xerocare range covers all the needs of dry skin: cleansing gel with 2% urea, body cream with 10% urea, and 40% urea cream for extremely rough areas.
Highlights:
Gentle cleansing Nutrition Daily protection
Cristescu Oana

Cristescu Oana

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Gyniclinique

Intensive Care for Rough Areas

The 40% Urea cream is an intensive solution for very dry, thickened, or calloused areas such as heels, elbows, and knees. At this concentration, urea acts as a powerful keratolytic: it softens the corneous layer, promotes skin regeneration, and restores smoothness. The fragrance- and colorant-free f...
Highlights:
40% Urea Softens skin Restores smoothness
Stanciu Diana Elena

Stanciu Diana Elena

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Amamed Clinics Miroslava

Natural Barrier Repair

With Xerocare, the skin barrier is restored, and the skin regains its hydration and natural comfort.
Highlights:
Hydration Elasticity Comfort
Denisa Diaconu

Denisa Diaconu

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Regina Maria

Daily Hydration and Repair

The urea in Xerocare cream not only hydrates but also repairs dry skin, restores the natural barrier, and provides lasting comfort, leaving the skin healthy and calm.
Highlights:
10% Urea Natural barrier Comfort
Tincu Diana

Tincu Diana

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Rmn Diagnostica

Intensive Keratolytic Treatment

XEROCARE UREA 40% EFFECT KERATOLITIC INTENS — removes calluses and thickened skin on heels and elbows efficiently.
Highlights:
40% Urea Calluses Regeneration
Edith Noemi Popirtan

Edith Noemi Popirtan

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Derma Elite

Care for Sensitive Skin

Sensitive skin deserves the gentlest care. Xerocare is the right choice.
Highlights:
Xerocare Dry skin Protection
Elena Popa

Elena Popa

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Cronos Med

Visible Results

Xerocare Anti-Callosity Cream with 40% Urea softens, smooths, and visibly improves the texture of thickened skin on heels, elbows, and knees, thanks to the synergy of Urea, Allantoin, and Shea Butter. Fragrance-free.
Highlights:
Fragrance-free Dry skin needs Urea
Andreea Domniteanu

Andreea Domniteanu

Verified clinician ✓

Specialty Dermatologist

Intense Hydration and Repair

Contains urea in a high concentration, making it very effective for thickened or calloused skin, such as heels and elbows. It softens and intensely hydrates the skin, restoring comfort. I recommend it for patients with very dry or calloused skin.
Highlights:
Concentrated urea Dry skin Calluses
Monica Paun

Monica Paun

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Dermo Medical Center & Illuma Clinique

Intensive Cream 40% Urea

An intensive cream with 40% urea, designed to effectively remove calluses and smooth rough, thickened skin on the feet, leaving it soft and even.
Highlights:
Keratolytic Smooth skin Calluses
Andreea Mintas

Andreea Mintas

Verified clinician ✓

Specialty Phd. Specialist Doctor in Dermatology and Venereology
Medical Institution Firstmed Budapesta

Thick Skin Treatment

My favorite product from the Xerocare range, ideal for thickened or cracked skin on the soles and heels — also recommended as a local occlusive dressing. Patients with thick scales or psoriasis vulgaris noticed quick improvement within days of use. Perfect for treating calluses on the palms and fe...
Highlights:
Psoriasis vulgaris Calluses Rapid repair
Popa Cristina

Popa Cristina

Verified clinician ✓

Specialty Specialist Doctor in Dermatology and Venereology
Medical Institution Prima Clinic

Radiance and Balance

True beauty is not about perfection, but about health and natural glow. Synergy Therm provides luminosity, deep hydration, and regeneration for a complexion that shines authentically.
Highlights:
Deep hydration Natural regeneration Healthy glow

Why is Xerocare Anti-Calluses Cream with 40% Urea, Allantoin & Shea Butter perfect for you?

Severe calluses (localized hyperkeratosis)

Softens and reduces thickened skin (heels, soles, palms, elbows)

Cracked heels (superficial fissures)

Exfoliates the thickened stratum corneum and softens cracks

Palmoplantar keratoderma

Supports treatment in conditions with excessive thickening of the skin on palms and soles

Chronic psoriasis with marked thickening

Can be applied locally on thick psoriatic plaques to help reduce scaling

Pre-procedural skin softening

Prepares skin before dermatological procedures (e.g., curettage, cryotherapy, or wart removal)

Clinical efficacy
Visible results in just 11 days of use:

+58% more hydrated skin in 11 days*

Skin feels smoother with fewer rough, hard patches.

100% felt their skin was hydrated*

Texture visibly improved with a quick softening effect.

100% softer heels*

Cracks diminished and skin looked healthier.

100% protection against moisture loss*

Feelings of dryness and tightness gradually decreased.

100% comfort & soothing*

Skin looked cared for and revitalized, even on problem areas.

95% suitable for dry/very dry skin

* Data from a clinical self-assessment study (N=22) with daily use for 8–11 days. Hydration increased by +43% after 8 days and +58% after 11 days. 100% reported a sensation of hydration, protection against dehydration, comfort and soothing, and softer heels. Results are subjective and may vary.

Key active ingredients & benefits

40% Urea

Strong keratolytic effect that exfoliates and reduces thickened, calloused skin

Allantoin

Supports healing of cracked or compromised skin

Shea Butter

A natural emollient rich in essential fatty acids and vitamins A, E, and F

Suitable for:

Areas with thickened, cracked, or severely calloused skin (heels, soles, palms, elbows)

Soles with superficial or painful fissures

Localized hyperkeratosis (excessive thickening of the stratum corneum)

Palmoplantar keratoderma (thickened skin on the palms and soles)

Thick psoriatic plaques in a chronic stage

Skin preparation before dermatological procedures (curettage, cryotherapy, wart removal)

Not recommended for sensitive skin or for use on large areas of the body.

How to use

Cleanse

Ensure the area is clean and dry

Apply

Apply locally to affected areas twice daily, using a small amount.

When

Preferably in the evening

Frequency

Daily, or as directed

Avoid

Use on sensitive skin or large body areas

How the formula works

High-concentration urea exfoliates rough skin, softens thickened areas, and helps reduce discomfort

Allantoin promotes tissue regeneration and accelerates skin repair

Shea butter provides deep nourishment and forms a protective layer to retain moisture

How "clean" is Xerocare Anti-Calluses Cream with 40% Urea, Allantoin & Shea Butter – 50ml?

Before and After

  • Frequently Asked Questions
Is this cream suitable for sensitive skin or use on the entire body?

No, due to the high urea concentration, it is intended for localized application only and not recommended for sensitive or compromised skin.

When should I apply it?

Ideally in the evening, on clean and dry skin, to allow maximum absorption and overnight action.

How long before I see results?

Visible improvement can occur within the first 7–10 days of consistent use.

Can it be used alongside dermatological treatments?

Yes, it can be used as a preparatory step to soften skin before procedures like cryotherapy, curettage, or wart removal.

Is it effective for psoriatic plaques?

Yes, it can be applied locally to thickened psoriatic plaques to help reduce scaling and discomfort.

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